Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death.

doi:10.1016/0140-6736(93)92064-z

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Article

Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death.

Lancet (London, England) - 30 Oct 1993

Marian A J, Yu Q T, Workman R, Greve G, Roberts R

Abstract excerpt

We determined the distribution frequency of angiotensin converting enzyme (ACE) polymorphism in 100 patients with hypertrophic cardiomyopathy and 106 of their unaffected siblings and offspring. The distribution of ACE genotypes was different in the two groups: allele D frequency of 0.69 in patien...

Topics

Alleles
Cardiomyopathy, Hypertrophic
Death, Sudden, Cardiac
Genotype
Humans
Peptidyl-Dipeptidase A
Polymerase Chain Reaction
Polymorphism, Genetic

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