Article
Involvement of SPI-2-encoded SpiC in flagellum synthesis in Salmonella enterica serovar Typhimurium.
BMC microbiology - 25 Aug 2009
Uchiya Kei-ichi, Sugita Asami, Nikai Toshiaki
Abstract excerpt
BACKGROUND: SpiC encoded within Salmonella pathogenicity island 2 on the Salmonella enterica serovar Typhimurium chromosome is required for survival within macrophages and systemic infection in mice. Additionally, SpiC contributes to Salmonella-induced activation of the signal transduction pathways in macrophages by affecting the expression of FliC, a component of flagella filaments. Here, we show the...
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