Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network

doi:10.3389/fcimb.2019.00270

Article

Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network

31 Jul 2019

Abstract excerpt

Salmonella species can infect a diverse range of birds, reptiles and mammals, including humans. The type III protein secretion system (T3SS) encoded by Salmonella pathogenicity island 1 (SPI-1) delivers effector proteins required for intestinal invasion and the production of enteritis. The T3SS is regarded as the most important virulence factor of Salmonella. SPI-1 encodes transcription factors that regulate the...

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