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Article

Effect of salt concentration on the pKa of acidic residues in lysozyme.

Journal of biochemistry - 1 Nov 1995

Abe Y, Ueda T, Iwashita H, Hashimoto Y, Motoshima H, Tanaka Y, Imoto T

Abstract excerpt

We determined the pKa values of acidic residues in hen lysozyme by comparing the pH dependency of stability between wild type and mutant lysozymes in which a negative charge is eliminated. In the comparison of the stability between wild type and a mutant lysozyme, the difference in pH titration curve between them could be expressed as a two-state process involving protonation of a single acidic residue. The...

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Identifiers

PMID: 8749311
DOI: 10.1093/jb/118.5.946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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