Article
pH dependence of antibody/lysozyme complexation.
Biochemistry - 16 Dec 1997
Gibas C J, Subramaniam S, McCammon J A, Braden B C, Poljak R J
Abstract excerpt
Association between proteins often depends on the pH and ionic strength conditions of the medium in which it takes place. This is especially true in complexation involving titratable residues at the complex interface. Continuum electrostatics methods were used to calculate the pH-dependent energetics of association of hen egg lysozyme with two closely related monoclonal antibodies raised against it and the...
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