Article
Association analysis of vitamin D receptor gene polymorphisms with bone mineral density in young women with Graves' disease.
Acta biochimica Polonica - 1 Jan 2008
Horst-Sikorska Wanda, Ignaszak-Szczepaniak Magdalena, Marcinkowska Michalina, Kaczmarek Marta, Stajgis Malgorzata, Slomski Ryszard
Abstract excerpt
UNLABELLED: Graves' (GD) hyperthyroidism induces accelerated bone turnover that leads to decreased bone mineral density (BMD). The role of the VDR gene in predisposition to primary osteoporosis has been recognized. Recent studies show associations between the VDR gene polymorphisms and susceptibility to autoimmune diseases. Here we analyzed if VDR gene polymorphisms: BsmI, ApaI, TaqI, and FokI may predispose...
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