Article
Variation in phenotypic appearance of Graves' disease: effect of genetic anticipation and duration of complaints.
European journal of endocrinology - 1 Jul 2009
Vos Xander G, Smit Natalie, Endert Erik, Tijssen Jan G P, Wiersinga Wilmar M
Abstract excerpt
OBJECTIVE: Both genetic and environmental factors contribute to susceptibility of Graves' disease. In this study, we evaluated whether the duration of symptoms or a positive family history of autoimmune thyroid disease (AITD) are related to specific phenotypes in patients with a first episode of Graves' hyperthyroidism (GH). DESIGN: Cross-sectional multicentre observational study. PATIENTS: Two hundred and...
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