Phenotype of in vitro human otosclerotic cells and its modulation by TGF beta.

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Article

Phenotype of in vitro human otosclerotic cells and its modulation by TGF beta.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Dec 1995

Bodo M, Venti G, Baroni T, Bellucci C, Giammarioli M, Donti E, Paludetti G, Stabellini G, Carinci P

Abstract excerpt

A study was carried out to obtain a more detailed picture of the phenotypes of human otosclerotic and normal bone cells and to analyse the response of both populations to treatment with TGF beta 1. Total collagen synthesis was found to be decreased, but fibronectin secretion increased in otoscler...

Topics

Bone and Bones
Cells, Cultured
Chondroitin Sulfates
Collagen
Dermatan Sulfate
Fibronectins
Glycosaminoglycans
Humans
Hyaluronic Acid
In Vitro Techniques
Otosclerosis
Phenotype
Transforming Growth Factor beta

Source

Open in PubMed

Identifiers

PMID: 8747085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8747085-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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