Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration in cholesteatoma fibroblasts: induction of neoplastic-like phenotype.

The American journal of otology - 1 Mar 1993

Parisier S C, Agresti C J, Schwartz G K, Han J C, Albino A P

Abstract excerpt

Cholesteatomas are invasive, locally destructive skin-like lesions that, after operative removal, have a significant recidivistic rate. These aggressive characteristics suggest a fundamental alteration in the biology of one or more of its constituents (i.e., keratinocytes, fibroblasts, and inflammatory cells). The cholesteatoma matrix was studied by subculturing it into its main cellular components. Short-term...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Adolescent
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Child, Preschool

Share to Fibroblasts

Share to Neoplasm Invasiveness

Share to Phenotype

Source

Identifiers

PMID: 8503484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Alteration in cholesteatoma fibroblasts: induction of neoplastic-like phenotype.PMID 8503484Read ↗

Characterization of primary cultures of cholesteatoma-associated fibroblasts.Semantic proximity Read ↗

Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.Semantic proximity Read ↗

The nature of the epithelium in acquired cholesteatoma: Part 3--Cytokeratin patterns in aural epithelial and cholesteatoma cells grown in cell culture.Semantic proximity Read ↗

Chronic inflammation of middle ear cholesteatoma promotes its recurrence via a paracrine mechanismSemantic proximity Read ↗

Cholesteatoma Growth and ProliferationSemantic proximity Read ↗

Cholesteatoma-associated fibroblasts modulate epithelial growth and differentiation through KGF/FGF7 secretion.Semantic proximity Read ↗

Aberrant expression of epidermal growth factor receptor in aural cholesteatomaSemantic proximity Read ↗

Establishment of ameloblastoma cell line, AM‐1Semantic proximity Read ↗

Keratoacanthoma: a tumor in search of a classification.Semantic proximity Read ↗

Phenotype of in vitro human otosclerotic cells and its modulation by TGF beta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.