Article
Relation between renin-angiotensin-aldosterone system and otosclerosis: a genetic association and in vitro study.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Apr 2008
Imauchi Yutaka, Jeunemaître Xavier, Boussion Magali, Ferrary Evelyne, Sterkers Olivier, Grayeli Alexis Bozorg
Abstract excerpt
OBJECTIVE/HYPOTHESIS: Angiotensin II (Ang II) may be implicated in the regulation of bone remodeling, and its activity is related to several gene polymorphisms including AGT M235T for plasmatic and tissular concentrations of angiotensinogen (AGT), ACE I/D for the angiotensin-converting enzyme activity, and AT(1)R A/C(1166) for the Ang II receptor function. The objective of this study was to investigate the...
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