Article
Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins.
Current opinion in lipidology - 1 Apr 1996
Mackness M I, Mackness B, Durrington P N, Connelly P W, Hegele R A
Abstract excerpt
Human serum paraoxonase is located on an HDL. It has the capacity to retard the accumulation of lipid peroxides in LDL under oxidizing conditions in vitro. Paraoxonase has a genetic polymorphism that results in a single amino acid substitution. Evidence indicates that both the serum concentration...
Topics
- 1-Alkyl-2-acetylglycerophosphocholine Esterase
- Animals
- Aryldialkylphosphatase
- Esterases
- Genotype
- Humans
- Insecticides
- Kinetics
- Lipoproteins
- Organophosphorus Compounds
- Phosphatidylcholine-Sterol O-Acyltransferase
- Phospholipases A
- Structure-Activity Relationship
