Article
Angiotensin II enhances glomerular expression of a nonmuscle myosin heavy chain, SMemb, with extracellular matrix accumulation.
Nephron - 1 Apr 2002
Mise Naobumi, Kimura Kenjiro, Kurabayashi Masahiko, Nagai Ryozo, Okuda Toshihiro, Ohba Shigeyoshi, Suzuki Naoe, Miyashita Kazuhisa, Kamijo Atsuko, Tojo Akihiro, Goto Atsuo, Omata Masao
Abstract excerpt
BACKGROUND/AIMS: We previously showed that the mesangial expression of nonmuscle-type myosin heavy chain, SMemb, was related to glomerular sclerosis. Although angiotensin II (AII) is known to promote the glomerular accumulation of extracellular matrix and sclerosis, the effect of AII on the mesan...
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