Article
Rapid allelic diversification and intensified selection at antigen recognition sites of the Mhc class II DPB1 locus during hominoid evolution.
Tissue antigens - 1 Mar 1996
Gyllensten U, Bergström T, Josefsson A, Sundvall M, Erlich H A
Abstract excerpt
The evolution of polymorphism at the Mhc class II DPB1 locus was studied by comparison of chimpanzee (Pan troglodytes), pygmy chimpanzee (Pan paniscus), gorilla (Gorilla gorilla) and human DPB1 alleles. Extensive polymorphism was found in all hominoids. The clustering of sequences in the phylogen...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cercopithecidae
- Epitopes
- Evolution, Molecular
- Genes, MHC Class II
- Gorilla gorilla
- HLA-DP Antigens
- HLA-DP beta-Chains
- Humans
- Macaca mulatta
- Molecular Sequence Data
- Pan troglodytes
- Phylogeny