Article
Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.
Gastroenterology - 1 Aug 1997
Squadrito G, Leone F, Sartori M, Nalpas B, Berthelot P, Raimondo G, Pol S, Bréchot C
Abstract excerpt
BACKGROUND & AIMS: Mutations in hepatitis C virus (HCV) nonstructural protein 5A (NS5A) may correlate with response to interferon in Japanese patients with chronic hepatitis C. The aim of this study was to examine whether these findings could be expanded to European patients infected with genotyp...
Topics
- Adult
- Amino Acid Sequence
- Antiviral Agents
- Base Sequence
- Chronic Disease
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Interferon-alpha
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA, Viral
- Viral Nonstructural Proteins