Article
Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus.
Journal of medical virology - 1 Aug 1999
Chung R T, Monto A, Dienstag J L, Kaplan L M
Abstract excerpt
A striking association has been demonstrated recently between mutations in amino acid residues 2209-2248 of the nonstructural protein 5a (NS5a) region of hepatitis C virus (HCV) and sustained responses to interferon in Japanese patients infected with genotype 1b. Therefore, analysis of this sequence has been suggested as a predictor of treatment response. We sought to determine whether mutations in this region...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
