Article
NS5A mutations predict biochemical but not virological response to interferon-alpha treatment of sporadic hepatitis C virus infection in European patients.
Journal of viral hepatitis - 1 Jul 2001
Stratidaki I, Skoulika E, Kelefiotis D, Matrella E, Alexandrakis G, Economou A, Kouroumalis E
Abstract excerpt
The NS5A region of the hepatitis C virus (HCV) genome has been reported by Japanese but not European investigators to be a significant factor in predicting interferon (IFN) response patients with HCV of genotype 1. We correlated the NS5A region with treatment outcome in patients with sporadic HCV infection. Twenty-eight patients (10 men, 18 women, mean age 60 +/- 2 years) with histologically proven HCV chronic...
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