Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional properties of a conditionally phenotypic, estrogen-responsive, human osteoblast cell line.

Journal of cellular biochemistry - 1 Jun 1997

Bodine P V, Green J, Harris H A, Bhat R A, Stein G S, Lian J B, Komm B S

Abstract excerpt

Osteoblasts are established targets of estrogen action in bone. We screened 66 conditionally immortalized clonal human osteoblast cell lines for estrogen receptors (ERs) using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for ER alpha mRNA and transactivation of adenovirus-estrogen response element (ERE)-tk-luciferase by 17 beta-estradiol (17 beta-E2) for functional ER protein. One of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cell Division
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line, Transformed

Share to Gene Expression

Share to Phenotype

Share to Polymerase Chain Reaction

Share to Temperature

Source

Identifiers

PMID: 9138093
DOI: 10.1002/(sici)1097-4644(19970601)65:3<368::aid-jcb7>3.0.co;2-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional properties of a conditionally phenotypic, estrogen-responsive, human osteoblast cell line.PMID 9138093Read ↗

Development and characterization of a conditionally transformed adult human osteoblastic cell line.Semantic proximity Read ↗

Development and characterization of conditionally immortalized osteoblast precursor cell lines from human bone marrow stroma.Semantic proximity Read ↗

Development and characterization of a conditionally immortalized human fetal osteoblastic cell line.Semantic proximity Read ↗

Estrogen receptor isoform‐specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβSemantic proximity Read ↗

Induction of Osteoblast Differentiation by Selective Activation of Kinase-Mediated Actions of the Estrogen ReceptorSemantic proximity Read ↗

Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts.Semantic proximity Read ↗

ER Gene Expression in Human Primary Osteoblasts: Evidence for the Expression of Two Receptor ProteinsSemantic proximity Read ↗

Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression.Semantic proximity Read ↗

Regulation of human cbfa1 gene transcription in osteoblasts by selective estrogen receptor modulators (SERMs)Semantic proximity Read ↗

Estrogen Promotes Early Osteoblast Differentiation and Inhibits Adipocyte Differentiation in Mouse Bone Marrow Stromal Cell Lines that Express Estrogen Receptor (ER) orSemantic proximity Read ↗

Estrogen Receptor α and β Heterodimers Exert Unique Effects on Estrogen- and Tamoxifen-Dependent Gene Expression in Human U2OS Osteosarcoma CellsSemantic proximity Read ↗

Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.