Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins.

doi:10.1128/JVI.66.6.3306-3315.1992

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Article

Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins.

Journal of virology - 1 Jun 1992

Gabuzda D H, Lever A, Terwilliger E, Sodroski J

Abstract excerpt

The role of the cytoplasmic domain of the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins in virus replication was investigated. Deletion of residues 840 to 856 at the carboxyl terminus of gp41 reduced the efficiency of virus entry during an early step in the virus life cycle b...

Topics

Acquired Immunodeficiency Syndrome
Base Sequence
CD4 Antigens
Cells, Cultured
DNA Mutational Analysis
Giant Cells
HIV Envelope Protein gp41
HIV-1
Molecular Sequence Data
Mutation
Protein Conformation
Protein Processing, Post-Translational
Proviruses
T-Lymphocytes
Viral Envelope Proteins
Virion
Virus Replication

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Identifiers

PMID: 1583717
DOI: 10.1128/JVI.66.6.3306-3315.1992
PMCID: PMC241108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1583717-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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