Article
Mutations in the core promoter/enhancer II regions of naturally occurring hepatitis B virus variants and analysis of the effects on transcription activities.
Intervirology - 1 Jan 1995
Nishizono A, Hiraga M, Kohno K, Sonoda Y T, Terao H, Fujioka T, Nasu M, Mifune K
Abstract excerpt
The regulatory regions for transcription and replication of several hepatitis B virus (HBV) genomes from 19 patients having various forms of HBV infection were sequenced. Predominant mutations were found to occur naturally in nucleotide positions 1762 (A to T) and 1764 (G to A) in chronic hepatitis patients and in asymptomatic carriers after seroconversion, but were not observed in HBeAg-positive healthy...
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