Article
Genetic studies of the PRP17 gene of Saccharomyces cerevisiae: a domain essential for function maps to a nonconserved region of the protein.
Genetics - 1 May 1996
Seshadri V, Vaidya V C, Vijayraghavan U
Abstract excerpt
The PRP17 gene product is required for the second step of pre-mRNA splicing reactions. The C-terminal half of this protein bears four repeat units with homology to the beta transducin repeat. Missense mutations in three temperature-sensitive prp17 mutants map to a region in the N-terminal half of...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Conserved Sequence
- DNA Primers
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Genotype
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype
- RNA Splicing
- RNA Splicing Factors
- RNA, Messenger
- RNA, Small Nuclear
- RNA-Binding Proteins
- Restriction Mapping