Article
[The characteristics of the transport into the nucleus of conjugates with normal and mutant nucleophilic sequences].
Tsitologiia - 1 Jan 1995
Barbul A I, Goriunov D E, Maĭboroda O A, Vinogradova N A, Skovorodkin I N, Nikol'skiĭ N N
Abstract excerpt
A study was made of the transport of conjugates of a fluorescently labeled protein and a synthetic peptide, corresponding to the nuclear localization sequence of the SV 40 large T-antigen, into the nuclei of cultured human (HeLa and A431) and murine (HER14) cells. A possibility for such conjugates to be transported into the nuclei of digitonin-permeabilized cells, without addition of exogenous cytosol, was...
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