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Article

Signal-mediated nuclear transport in simian virus 40-transformed cells is regulated by large tumor antigen.

15 Nov 1992

Abstract excerpt

Transformation of cultured cells with simian virus 40 (SV40), or transfection with the early region of the SV40 genome, causes a significant increase in both the rate of signal-mediated nuclear transport and the functional size of the transport channels (located in the pore complexes). By microinjecting purified large tumor (T) antigen into the cytoplasm of murine BALB/c 3T3 cells, we have demonstrated that this...

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Identifiers

PMID: 1279701
DOI: 10.1073/pnas.89.22.11002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Signal-mediated nuclear transport in simian virus 40-transformed cells is regulated by large tumor antigen.PMID 1279701Read ↗

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