Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.

doi:10.1128/JVI.70.9.6012-6019.1996

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Article

Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.

Journal of virology - 1 Sept 1996

Fickenscher H, Biesinger B, Knappe A, Wittmann S, Fleckenstein B

Abstract excerpt

Herpesvirus saimiri strain C488, a T-cell tumor virus of New World primates, transforms human T lymphocytes to stable interleukin-2-dependent growth without need for further stimulation by antigen or mitogen. The transformed cell lines show the phenotype of activated mature T cells and retain man...

Topics

Amino Acid Sequence
Animals
Antibodies
Callithrix
Cell Line, Transformed
Cell Transformation, Viral
Cysteine
Gene Expression Regulation, Viral
Genes, Immediate-Early
Herpesvirus 2, Saimiriine
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-2

Lymphocyte Activation

Molecular Sequence Data

Oncogenes

Peptides

Phenotype

Phosphoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 8709223
DOI: 10.1128/JVI.70.9.6012-6019.1996
PMCID: PMC190621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8709223-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.PMID 8709223Read ↗

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