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Article

T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation.

Journal of virology - 1 May 2005

Heck Elke, Lengenfelder Doris, Schmidt Monika, Müller-Fleckenstein Ingrid, Fleckenstein Bernhard, Biesinger Brigitte, Ensser Armin

Abstract excerpt

Herpesvirus saimiri (saimirine herpesvirus 2) (HVS), a T-lymphotropic tumor virus, induces lymphoproliferative disease in several species of New World primates. In addition, strains of HVS subgroup C are able to transform T cells of Old World primates, including humans, to permanently growing T-cell lines. In concert with the Stp oncoprotein, the tyrosine kinase-interacting protein (Tip) of HVS C488 is required...

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Share to Cell Transformation, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15827186
DOI: 10.1128/JVI.79.9.5713-5720.2005
PMCID: PMC1082769

Genes

STAT3
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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