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Article

Human immunodeficiency virus type 1 Vpr modifies cell proliferation via multiple pathways.

Microbiology and immunology - 1 Jan 1999

Yamaguchi T, Watanabe N, Nakauchi H, Koito A

Abstract excerpt

Vpr, one of the accessory molecules of HIV-1, has been demonstrated to arrest the cell cycle at the G2 phase. This Vpr-mediated cell cycle arrest is implicated to have an important role in the viral life cycle. In the present study, we quantitate the extent of Vpr-mediated cell cycle arrest with the use of a bicistronic vector consisting of a vpr gene and a green fluorescence protein sequence. Using this system,...

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Identifiers

PMID: 10449250
DOI: 10.1111/j.1348-0421.1999.tb02427.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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