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Article

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

1 Aug 1996

Abstract excerpt

The cornified envelope is a layer of transglutaminase cross-linked protein that is deposited under the plasma membrane of keratinocytes in the outermost layers of the epidermis. We present the sequence of one of the cornified envelope precursors, a protein with an apparent molecular mass of 210 kD. The 210-kD protein is translated from a 6.5-kb mRNA that is transcribed from a single copy gene. The mRNA was...

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PMID: 8707850
DOI: 10.1083/jcb.134.3.715

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.PMID 8707850Read ↗

Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of the epidermal cornified envelope.Semantic proximity Read ↗

S100A11, S100A10, Annexin I, Desmosomal Proteins, Small Proline-rich Proteins, Plasminogen Activator Inhibitor-2, and Involucrin Are Components of the Cornified Envelope of Cultured Human Epidermal KeratinocytesSemantic proximity Read ↗

Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentinSemantic proximity Read ↗

SPRR4, a novel cornified envelope precursor: UV-dependent epidermal expression and selective incorporation into fragile envelopesSemantic proximity Read ↗

Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrierSemantic proximity Read ↗

Loss of desmoplakin tail causes lethal acantholytic epidermolysis bullosa.Semantic proximity Read ↗

Identification of Late Differentiation Antigens of Human Cornified Epithelia, Expressed in Re-Organized Desmosomes and Bound to Cross-Linked EnvelopeSemantic proximity Read ↗

Analysis of the desmoplakin gene reveals striking conservation with other members of the plakin family of cytolinkers.Semantic proximity Read ↗

Suprabasin, a Novel Epidermal Differentiation Marker and Potential Cornified Envelope PrecursorSemantic proximity Read ↗

cDNA Cloning of the 210-kDa Paraneoplastic Pemphigus Antigen Reveals that Envoplakin Is a Component of the Antigen ComplexSemantic proximity Read ↗

Human stratum corneum proteomics reveals cross‐linking of a broad spectrum of proteins in cornified envelopesSemantic proximity Read ↗

Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin: members of a new gene family involved in organization of intermediate filamentsSemantic proximity Read ↗

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