Article
Human stratum corneum proteomics reveals cross‐linking of a broad spectrum of proteins in cornified envelopes
28 Mar 2019
Abstract excerpt
Defects in keratinocyte transglutaminase (TGM1), resulting in an improper protein scaffold for deposition of the lipid barrier, comprise a major source of autosomal recessive congenital ichthyosis. For that reason, the composition and formation of the cornified (cross-linked) protein envelope of the epidermis have been of considerable interest. Since the isopeptide cross-linked protein components are not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.