Article
Identification of N-acetylglucosamine binding residues in Griffonia simplicifolia lectin II.
FEBS letters - 29 Jul 1996
Zhu K, Bressan R A, Hasegawa P M, Murdock L L
Abstract excerpt
Primary structure and crystallographic data of several legume lectins were used to predict the involvement in carbohydrate binding of six amino acid residues (Asp88, Glu108, Tyr134, Asn136, Leu226 and Gln227) in Griffonia simplicifolia lectin II (GS-II). The functional involvement of these residues was evaluated by assessing GlcNAc binding of modified forms of GS-II in which these residues were eliminated in...
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