Article
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference.
BMC structural biology - 1 Jun 2007
Adam Jan, Pokorná Martina, Sabin Charles, Mitchell Edward P, Imberty Anne, Wimmerová Michaela
Abstract excerpt
BACKGROUND: Lectins are proteins of non-immune origin capable of binding saccharide structures with high specificity and affinity. Considering the high encoding capacity of oligosaccharides, this makes lectins important for adhesion and recognition. The present study is devoted to the PA-IIL lectin from Pseudomonas aeruginosa, an opportunistic human pathogen capable of causing lethal complications in cystic...
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