Article
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis.
Nature medicine - 1 Aug 1996
Callan M F, Steven N, Krausa P, Wilson J D, Moss P A, Gillespie G M, Bell J I, Rickinson A B, McMichael A J
Abstract excerpt
Primary infection with Epstein-Barr virus often results in the clinical syndrome of acute infectious mononucleosis (glandular fever). This illness is characterized by a striking lymphocytosis, the nature of which has been controversial. We show that large monoclonal or oligoclonal populations of...
Topics
- Acute Disease
- Amino Acid Sequence
- Base Sequence
- CD8-Positive T-Lymphocytes
- Clone Cells
- DNA
- Herpesvirus 4, Human
- Humans
- Infectious Mononucleosis
- Molecular Sequence Data
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta