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Article

Cloning and Characterization of an Alternatively Processed Human Type II Interleukin-1 Receptor mRNA

1 Aug 1996

Abstract excerpt

Two types of interleukin (IL)-1 receptors with three extracellular immunoglobulin-like domains, limited homology (28%), and different pharmacological characteristics termed type I and type II have been cloned from mouse and human cell lines. Both receptors exist in transmembrane and soluble forms; the soluble IL-1 receptor is thought to be post-translationally derived from cleavage of the extracellular portion of...

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PMID: 8702856
DOI: 10.1074/jbc.271.34.20965

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