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Article

A human transforming growth factor-beta type II receptor that contains an insertion in the extracellular domain.

Experimental cell research - 25 Feb 1996

Hirai R, Fijita T

Abstract excerpt

In the signal transduction of transforming growth factor-beta (TGF-beta), the TGF-beta type II receptor (betaR-II) binds TGF-beta, presents the ligand to type I receptor, and forms a heterodimeric receptor complex that functions as an active signaling receptor. We isolated cDNA clones encoding an isoform of human betaR-II from vascular endothelial cells by RT-PCR. The deduced structure of the isoform designated...

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Identifiers

PMID: 8635485
DOI: 10.1006/excr.1996.0066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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