Article
Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition.
Proceedings of the National Academy of Sciences of the United States of America - 16 Aug 1994
Xu J, Matsuzaki K, McKeehan K, Wang F, Kan M, McKeehan W L
Abstract excerpt
Heterodimers of types I and II serine/threonine kinase receptor monomers compose the active receptor complex for ligands of the transforming growth factor beta family. Here we show that the genomic organization of coding sequences for the intracellular domain of a widely expressed type I serine/threonine kinase receptor is similar to that of the activin type II receptor gene. The genomic structure and cDNA clones...
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