Article
Fibronectin mRNA splice variant in articular cartilage lacks bases encoding the V, III-15, and I-10 protein segments.
The Journal of biological chemistry - 2 Aug 1996
MacLeod J N, Burton-Wurster N, Gu D N, Lust G
Abstract excerpt
Fibronectin is an extracellular matrix glycoprotein encoded by a single gene. Alternative RNA splicing has been reported at three sites, ED (extra type III domain)-A, ED-B, and the variable or V region. Articular cartilage fibronectin monomers are rarely (ED-A)+, but approximately 25% are (ED-B)+. RNA gel electrophoresis and Northern blot analysis identified two (ED-B)+ and two (ED-B)- fibronectin transcripts in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
