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Article

Alternative splicing of fibronectin: three variants, three functions.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1991

Schwarzbauer J E

Abstract excerpt

Fibronectin (FN) is a multi-functional extracellular matrix protein required for cell adhesion and migration, blood clotting, wound healing, and oncogenic transformation. The functional complexity is paralleled by structural diversity in that multiple forms of FN are generated by cell type-specific alternative splicing. In the rat, up to 12 different combinations of the three alternatively spliced segments...

Topics

Animals
Blood Coagulation
Cell Adhesion
Exons
Fibronectins
Genetic Variation
Humans
Macromolecular Substances
RNA Splicing
RNA, Messenger
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1755828
DOI: 10.1002/bies.950131006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1755828-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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