Article
Cell-specific expression of fibronectin and EIIIA and EIIIB splice variants after oxygen injury.
The American journal of physiology - 1 Apr 1998
Maniscalco W M, Watkins R H, Chess P R, Sinkin R A, Horowitz S, Toia L
Abstract excerpt
Cellular fibronectin (cFN) expression is characteristic of injured tissues. Unlike plasma FN, cFN mRNA often contains the EIIIA or EIIIB domains. We examined the lung cell-specific expression of total cFN mRNA and the EIIIA and EIIIB splice variants in rabbits after acute oxygen injury. By in situ hybridization, control lung had low cFN mRNA. After exposure to > 95% oxygen, mRNAs for total cFN and EIIIA were...
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