Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of EDA+ and EDB+ fibronectin splice variants in bone.

Bone - 1 Dec 2004

Kilian O, Dahse R, Alt V, Zardi L, Rosenhahn J, Exner U, Battmann A, Schnettler R, Kosmehl H

Abstract excerpt

The extracellular matrix component fibronectin (fn) has fundamental functions in cell attachment, differentiation, proliferation, and migration. Isoforms of cellular fibronectin, named EDA+ fibronectin or embryonal EDB+ fibronectin, are generated by alternative splicing of its mRNA precursors. Little is known about the expression of EDA+ and EDB+ fibronectin splice variants in human bone. The aim of this study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Bone and Bones
Share to Bone Remodeling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibronectins

Share to Mesenchymal Stem Cells

Share to Osteoblasts

Share to Osteosarcoma

Share to Protein Isoforms

Source

Identifiers

PMID: 15589214
DOI: 10.1016/j.bone.2004.08.008

Genes

EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of EDA+ and EDB+ fibronectin splice variants in bone.PMID 15589214Read ↗

Fibronectin mRNA splice variant in articular cartilage lacks bases encoding the V, III-15, and I-10 protein segments.Semantic proximity Read ↗

Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation.Semantic proximity Read ↗

Expression, localization and alternative splicing pattern of fibronectin messenger RNA in fibrotic human liver and hepatocellular carcinomaSemantic proximity Read ↗

Expression of Fibronectin Isoforms in Human Breast Tissue: Production of Extra Domain A<sup>+</sup>/Extra Domain B<sup>+</sup> by Cancer Cells and Extra Domain A<sup>+</sup> by Stromal CellsSemantic proximity Read ↗

New insights into form and function of fibronectin splice variants.Semantic proximity Read ↗

Age-dependent differential expression of fibronectin variants in skin and airway mucosal wounds.Semantic proximity Read ↗

The Fibronectin Extra Domain A Activates Matrix Metalloproteinase Gene Expression by an Interleukin-1-dependent MechanismSemantic proximity Read ↗

Human tenascin-C: Identification of a novel type III repeat in oral cancer and of novel splice variants in normal, malignant and reactive oral mucosaeSemantic proximity Read ↗

Inherent physical characteristics and gene expression differences between alveolar and basal bones.Semantic proximity Read ↗

Alternative splicing of the angiogenesis associated extra-domain B of fibronectin regulates the accessibility of the B-C loop of the type III repeat 8.Semantic proximity Read ↗

The alternatively spliced domains EIIIB and EIIIA of human fibronectin affect cell adhesion and spreadingSemantic proximity Read ↗

Alternative splicing of fibronectin: three variants, three functions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.