Article
Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains.
European journal of biochemistry - 1 Jul 2000
Dirusso C C, Connell E J, Faergeman N J, Knudsen J, Hansen J K, Black P N
Abstract excerpt
Saccharomyces cerevisiae is an ideal model eukaryote for studying fatty-acid transport. Yeast are auxotrophic for unsaturated fatty acids when grown under hypoxic conditions or when the fatty-acid synthase inhibitor cerulenin is included in the growth media. The FAT1 gene encodes a protein, Fat1p, which is required for maximal levels of fatty-acid import and has an acyl CoA synthetase activity specific for...
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