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Detection of an amino acid polymorphism in hormone-sensitive lipase in Japanese subjects.

Metabolism: clinical and experimental - 1 Jul 1996

Shimada F, Makino H, Hashimoto N, Iwaoka H, Taira M, Nozaki O, Kanatsuka A, Holm C, Langin D, Saito Y

Abstract excerpt

Hormone-sensitive lipase (HSL) plays an important role in energy metabolism by controlling the hydrolysis of triglycerides stored in adipose tissue. To investigate whether mutations in the HSL gene are associated with non-insulin-dependent diabetes mellitus (NIDDM), we screened for mutations of this gene using single-stranded conformation polymorphism (SSCP) in 35 Japanese subjects with NIDDM. SSCP analysis...

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Identifiers

PMID: 8692022
DOI: 10.1016/s0026-0495(96)90160-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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