Article
Association of allele-specific HLA expression and histopathologic progression of cervical carcinoma.
Gynecologic oncology - 1 Jul 1996
van Driel W J, Tjiong M Y, Hilders C G, Trimbos B J, Fleuren G J
Abstract excerpt
Immunohistochemical studies have shown that loss of HLA expression is observed in cervical carcinomas but not in premalignant CIN lesions, indicating that downregulation of HLA is linked to tumor progression. The present study was performed to investigate whether the degree of HLA expression in cervical cancer correlates with more advanced disease as defined by histopathological features. Frozen tissue sections...
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