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Article

From HPV Infection to Lesion Progression: The Role of HLA Alleles and Host Immunity

1 Jan 2019

Abstract excerpt

Persistent high-risk human papillomavirus (HPV) infection has been associated with increased risk for cervical precancerous lesions and cancer. The host's genetic variability is known to play a role in the development of cervical cancer. The human leukocyte antigen (HLA) genes are highly polymorphic and have shown to be important risk determinants of HPV infection persistence and disease progression. HLA class I...

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PMID: 30783048
DOI: 10.1159/000494985

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