Article
Implication of involvement of rat chromosome #2 in spontaneous transformation of the rat-2 cell line.
Cell biology international - 1 May 1996
Krishnaveni L, Ghosh S N
Abstract excerpt
Using an in vitro model for cell transformation, the relationship between specific chromosomal aberration and phenotypic changes was studied at different passages of Rat-2 cell line. A marker chromosome resulting from a translocation [t(2;7)] was found to be associated with focus formation in soft agar. Conversely, the loss of this marker chromosome was found to be associated with phenotypic reversion. These...
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