Article
[The karyotypic variability of mouse embryonic fibroblasts of 2 genotypes during spontaneous neoplastic transformation].
Tsitologiia - 1 Jan 1990
Glazko T T, Lavrovskiĭ V A
Abstract excerpt
Karyological analysis of 6 lines with distinct tumorigenic properties of mouse strains C3H/He and C57BL/6 has been carried out using a differential staining of chromosomes. The number of normal copies of chromosomes varied in all the investigated cell lines. The more and the less stable chromosomes different from line to line. All the cell lines were characterized by decreased numbers of copies of normal...
Topics
- Animals
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Cells, Cultured
- Embryo, Mammalian
- Fibroblasts
- Genetic Variation
- Genotype
- Karyotyping
- Mice
- Mice, Inbred C3H
