Article
[Features of rat cells karyotypic abnormalities in rat cells in their transformation in vitro].
Tsitologiia - 1 Jan 2014
Iartseva N M, Fedortseva R F
Abstract excerpt
Neoplastic transformation of cells is characterized by karyotypic abnormalities involving aneuploidy, quantitative changes, as well as multiple clonal rearrangements of the number and structure of chromosomes. It is probable that chromosomes are one of the mechanisms of cells immortalization and transformation. Despite many years of study of chromosomal rearrangements, data on primary chromosomal rearrangements...
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