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Article

Mutation in the structural gene for release factor 1 (RF-1) of Salmonella typhimurium inhibits cell division.

Journal of bacteriology - 1 Jul 1996

Olafsson O, Ericson J U, VanBogelen R, Björk G R

Abstract excerpt

A temperature-sensitive mutant of Salmonella typhimurium LT2 was isolated. At the nonpermissive temperature cell division stopped and multinucleated filaments were formed. DNA, RNA, or protein synthesis was not affected until after about two generations. Different physiological conditions, such as anaerobiosis and different growth media, suppress the division deficiency at high temperatures. Certain mutations...

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Identifiers

PMID: 8682787
DOI: 10.1128/jb.178.13.3829-3839.1996
PMCID: PMC232643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Mutation in the structural gene for release factor 1 (RF-1) of Salmonella typhimurium inhibits cell division.PMID 8682787Read ↗

Temperature sensitivity caused by mutant release factor 1 is suppressed by mutations that affect 16S rRNA maturation.Semantic proximity Read ↗

Thermoinducible filamentation in Escherichia coli due to an altered RNA polymerase beta subunit is suppressed by high levels of ppGpp.Semantic proximity Read ↗

A novel mutation in ribosomal protein S4 that affects the function of a mutated RF1.Semantic proximity Read ↗

Salmonella typhimurium prfA mutants defective in release factor 1.Semantic proximity Read ↗

Suppression of temperature-sensitive defects of polypeptide release factors RF-1 and RF-2 by mutations or by an excess of RF-3 in Escherichia coli.Semantic proximity Read ↗

Growth-dependent DNA breakage and cell death in a gyrase mutant of Salmonella.Semantic proximity Read ↗

Autogenous suppression of an opal mutation in the gene encoding peptide chain release factor 2.Semantic proximity Read ↗

Identification of Salmonella functions critical for bacterial cell division within eukaryotic cells.Semantic proximity Read ↗

Interactions of release factor RF3 with the translation machinery.Semantic proximity Read ↗

Genetic implication for an interaction between release factor one and ribosomal protein L7/L12 in vivo.Semantic proximity Read ↗

Sequence and functional analysis of mutations in the gene encoding peptide-chain-release factor 2 of Escherichia coli.Semantic proximity Read ↗

Altered translational fidelity of a Salmonella typhimurium LT2 mutant resistant to the aminoglycoside antibiotic neamine.Semantic proximity Read ↗

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