Article
Mutation in the structural gene for release factor 1 (RF-1) of Salmonella typhimurium inhibits cell division.
Journal of bacteriology - 1 Jul 1996
Olafsson O, Ericson J U, VanBogelen R, Björk G R
Abstract excerpt
A temperature-sensitive mutant of Salmonella typhimurium LT2 was isolated. At the nonpermissive temperature cell division stopped and multinucleated filaments were formed. DNA, RNA, or protein synthesis was not affected until after about two generations. Different physiological conditions, such a...
Topics
- Aldehyde Oxidoreductases
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cell Division
- Chromosome Mapping
- Chromosomes, Bacterial
- Genes, Bacterial
- Genes, Recessive
- Guanosine Tetraphosphate
- Heat-Shock Response
- Molecular Sequence Data
- Mutation
- Peptide Termination Factors
- Phenotype
- Protein Biosynthesis
- SOS Response, Genetics
- Salmonella typhimurium