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Article

Autogenous suppression of an opal mutation in the gene encoding peptide chain release factor 2.

Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 1990

Kawakami K, Nakamura Y

Abstract excerpt

The peptide chain release factor 2 (RF2) gene, prfB, was cloned from Salmonella typhimurium by DNA hybridization using the Escherichia coli prfB probe. The nucleotide and amino acid sequences of prfB are 87.0% and 95.6% homologous between E. coli and S. typhimurium, respectively, including an in-frame premature UGA stop codon at position 26, the site of +1 frameshift for mature RF2 synthesis. The supK584...

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Identifiers

PMID: 2236050
DOI: 10.1073/pnas.87.21.8432
PMCID: PMC54970

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