Article
Effects of overexpression of the transferrin receptor on the rates of transferrin recycling and uptake of non-transferrin-bound iron.
European journal of biochemistry - 1 Jun 1996
Callus B A, Iacopetta B J, Kühn L C, Morgan E H
Abstract excerpt
The possibilities that the recycling of the transferrin receptor is a rate-limiting step in the efflux of endocytosed transferrin, and that the receptor functions as a trans-membrane Fe transporter were investigated in untransfected Ltk- cells and in cells transfected with different levels of DNA...
Topics
- Animals
- Biological Transport
- Cell Line
- Endocytosis
- Gene Expression
- Hydrogen-Ion Concentration
- Iron
- Kinetics
- Mice
- Mutation
- Peptide Fragments
- Protein Binding
- Receptors, Cell Surface
- Receptors, Transferrin
- Transfection
- Transferrin