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Article

Mutations at the capsid-nucleocapsid cleavage site of gag polyprotein of Moloney murine leukemia virus abolish virus infectivity.

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Feb 1996

Housset V, Darlix J L

Abstract excerpt

Capsid protein CAp30 and nucleocapsid protein NCp10 of Moloney murine leukemia virus (MoMuLV) are the 2 major proteic components of the virion core and are generated by processing of the gag polyprotein precursor, Pr65gag, by the viral protease. In the virion core, several hundred NCp10 molecules are bound to the genomic RNA dimer forming the nucleocapsid structure. In the course of virus assembly, NC protein, as...

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PMID: 8680959

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