Article
Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A.
Science (New York, N.Y.) - 22 Oct 1993
Brunner H G, Nelen M, Breakefield X O, Ropers H H, van Oost B A
Abstract excerpt
Genetic and metabolic studies have been done on a large kindred in which several males are affected by a syndrome of borderline mental retardation and abnormal behavior. The types of behavior that occurred include impulsive aggression, arson, attempted rape, and exhibitionism. Analysis of 24-hour urine samples indicated markedly disturbed monoamine metabolism. This syndrome was associated with a complete and...
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