Article
Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif.
Genomics - 1 Jul 1992
Hinds H L, Hendriks R W, Craig I W, Chen Z Y
Abstract excerpt
The genes encoding the A and B forms of the human monoamine oxidase enzymes (MAOA and MAOB) are localized at Xp11.23-Xp11.4. We report the characterization of a highly informative polymorphic region within a 2.9-kb cloned fragment containing the first exon of the MAOA gene. The polymorphic region consists of a GT microsatellite directly adjacent to an imperfectly duplicated novel 23-bp VNTR motif. DNA sequencing...
Topics
- Alleles
- Base Sequence
- DNA Probes
- DNA, Satellite
- Exons
- Female
- Gene Frequency
- Humans
- Male
- Molecular Sequence Data
- Monoamine Oxidase
- Polymorphism, Genetic
